Tykerb 250 mg (Lapatinib)|novartis|uses,composition,side effects,price in India

                    TYKERB

DESCRIPTION

                                   Tykerb 250mg  belongs to class of antineoplastic drugs which preventsTykerb 250mg  the development Tykerb 250mg tablet and spreading of cancer cells all over the body.
Tykerb 250mg tablet is indicated forTykerb 250mg metastatic breast cancer and spreading after using of other chemotherapy drugs

TYKERB 250MG

 INDICATION

                                   Tykerb 250mg with combination of capecitabine is indicated for the treatment of advanced breast cancer after the failure of other Tykerb 250mg tabletcancer medicine.
Tykerb 250mg tablet is also combined with letrozole is indicated for the treatment postmenopausal women Tykerb 250mg tabletwith hormone receptor positive metastatic breast cancer.

MECHANISM OF ACTION

                              Tykerb 250mg tablet is a type of classification called kinase inhibitor and act by intracellular tyrosine kinase.
Tykerb prohibits ErbB-forced tumor cell growth in vitro and in various animal models. When Tykerb 250mg combination 5-fluracil with
Tykerb 250mg created an additive effect in the 4 tumor cell lines tested. Development inhibitsTykerb 250mg tablet the Tykerbtablet effect were examined
in trastuzumab-conditioned cell lines.
Tykerb 250mg tablet provide selective Tykerb 250mg action against breast cancer cell lines selected for long-term growth in trastuzumab-containing
intracellularly. HormoneTykerb 250mg tablet receptor-positive breast Tykerb 250mgcancer cells (with ER [Estrogen Receptor] and/or PgR [Progesterone Tykerb 250mg tabletReceptor])
that co express the HER2 bear toTykerb 250mg tablet be protection against established endocrine therapies. Synchronously
hormone receptor-positive Tykerb 250mg tablet breast cancer cells that initially lack EGFR or HER2 unrecalled these receptor proteins as the
tumor becomes resistant toTykerb 250mg tablet endocrine therapy.

PHARMACOKINETIC

ABSORPTION

                       Poor absorpsTykerb 250mg tablet from the GI tract. peak plasma concentration is approx 4hrs ; Tykerb 250mg bioavailability is 95%. Tykerb 250mg with food Tykerb 250mg tabletwill increase the systemic exposure.

DISTRIBUTION

                     Plasma Tykerb 250mg protein binding is 99%

METABOLISM

                  Tykerb 250mg tablet Metabolized mainly Tykerb 250mg by CYP3A4 and CYP3A5.

ELIMINATION

The Tykerb 250mg drug eliminatedTykerb 250mg tablet dose via feces more than 14% and <2% urine.
Eliminated half life is 24hrs.

PRODUCT DETAILS

Brand : Tykerb
Ingredients : Lapatinib
Strength : 250mg
Manufactured : Novartis India Ltd
Package : 30 Tablets
PRICE:Tykerb 250mg tablet ,Tykerb 250mg

DOSAGE AND ADMINISTRATION

                   The usual Tykerb 250mg tabletdose of Tykerb for adult suffering HER2 positive metastatic breast cancer
(with xeloda) is 1250mg Tykerb 250mg tabletonce daily for 1-21daysTykerb 250mg tablet continuously repeating.
Femara Combination with Tykerb the dose recommended is 1500mg orally once Tykerb 250mg tableta day continuosly once daily every day.
Take the Tykerb 250mg drug Tykerb tablet on Tykerb 250mg tabletan empty stomach(1hr before or 1hr after).

OVERDOSE

                    If overdose occurs, Tykerb 250mg tabletseek to emergency department or call poison control helpline

SIDE EFFECTS

                Tykerb 250mg tablet will cause mild to moderate side effects in patients. If symptoms causes Tykerb 250mg tabletserious theTykerb 250mg  inform the doctor as Tykerb 250mg tabletsoon as possible.

COMMON SIDE EFFECT OF TYKERB 250MG TABLET

                    Lumbar pain;Tykerb 250mg tablet diarrhae; dry skin; nail of finger toe changes; headache; in digestion problem ; Tykerb 250mg tabletdecreased appetite; mild hair loss or thinning;
mouth ulcers; nausea; nosebleed; Tykerb 250mg tabletredness and hands and Tykerb 250mg feet will have tingling; weakness; insomnia; vomiting.

SERIOUS SIDE EFFECT OF TYKERB 250MG TABLETS

                      Severe tightness;Tykerb 250mg tablet difficulty in breathing; unusual bruising or bleeding; unusual itching; yellowing of the eyes or skin;.
Chest pain; urine Tykerb 250mg tabletwill be dark; Tykerb 250mg dizziness or light-headedness; Tykerb 250mg Rapid or irregular heartbeat; pale stools; persistent loss of appetite;
severe or Tykerb 250mg tabletpersistent cough; severe or persistent diarrhea,



nausea, Tykerb 250mg tabletvomiting and skin allergy like itching, rashes, blisters in mouth, face,Tykerb 250mg tablet lip or tongue.

SAFETY PRECAUTIONS

                     If you are Tykerb 250mg tablet allergic to lapatinib, then do not use the drug
If you had hepatic problem, Tykerb 250mg cardio disease, an electrolytic imbalance then discuss with doctor whether it’s safe to use or not piror to Tykerb treatment.
While patients Tykerb 250mg during pregnancy,Tykerb 250mg it should strictly avoid the drug because it harm the unborn baby or cause birth defects.
There is not known whether Tykerb 250mg Lapatinib passes into breast milk. Hence avoid breast feeding to the infants during Tykerb treatment,

DRUG INSTRUCTION

                  Interation of Tykerb 250mg tablet with following drugs: Artemether,Etravirine,Pazopanib, Tracrolimus,Tykerb 250mg tablet Telithromycin,Topotecan,Tykerb 250mg tabletTramadol,Tretinoin, Tykerb 250mg Voriconazole, Ziprasidone. will increase risk of side effects and drug will not work properily and effect of Tykerb may changes.

PREGNANCY

                 Tykerb 250mg tablet has no adequate and well tolerated details about the drug Tykerb 250mg in Tykerb 250mg tablet pregnantTykerb 250mg women. Excretion into human milk is unknown. Avoid not become pregnant Tykerb 250mg tablet while receiving Tykerb treatment.

CONTRAINDICATION

                Tykerb 250mg is contraindicated Tykerb 250mg tablet to hypersensitivity condition Tykerb 250mg tablet and any products of recipients of Tykerb

STORAGE

                Do Tykerb 250mg not use the drug Tykerb 250mg tablet after the medication has expired. Keep away from the children. For Discarding the medicine, Tykerb 250mg it should discuss with pharmacist.Tykerb 250mg tablet for proper dispose of chemo drugs. Store at 25-30°C.

MISSED DOSE

                Take the missed Tykerb 250mg tablet dose as you remember soon Tykerb 250mg tablet before the next dose time. If time to next dose then skip the missed dose and go Tykerb 250mg tablet for daily Tykerb 250mg tablet schedule, don’t make up with extra dose. Please consult the doctorTykerb 250mg  for further details.

EMAIL ID        : millionhealthpharmaceuticals@gmail.com
CONTACT US : +91-9940472902
WEBSITE         : https://millionpharma.com/tykerb.php

KEYWORDS:Tykerb 250mg tablet ,Tykerb 250mg